Ademetionine disulfate tosylate CAS:97540-22-2
S-Adenosyl-l methionine Disulfate Tosylate (SAMe for short) is a common cosubstrate
involved in methyl group transfers. SAMe was first discovered in Italy by G. L.
Cantoni in 1952, can preventing liver cancer, promoting cartilaginous tissue forming
and concrescence, may help fight depression, alzheimer's disease, liver disease, and
the pain of osteoarthritis, is now universerally acknowleged as an important
pharmaceuticals to treat liver diseases. Nowaday it is commonly used
in pharmaceuticals, health care food industry both at domestic and international market.
Ademetionine disulfate tosylate COA
Test | Specifications | Result |
Appearance | Almost white powder,hygroscopic,soluble in water | Complies |
Identification | Chemical reaction IR:consistent with the spectrum obtained with reference substance HPLC:the retention time of a major peak meets the requirement | Positive Complies Comples |
Acid value | 1.0~2.0 | 1.6 |
Clarity and color of solution | Not more intensely colored than reference | Complies |
Heavey metals | ≤10ppm | Complies |
Water | ≤2.5% | 1.6% |
S-adenosyl-L-Homocystein | ≤0.5% | 0.05% |
Methithioadenosine Adenine (S,S) Isomer Endotoxin Microbiological P-toluenesulfonatic acid Sulfates Ademetionine Total content | ≤2.0% ≤0.5% ≥60.0% 0.3EU/mg 1000CFU/g 21.0%~24.0% 23.5~26.5% 49.5% 98% | 0.23% 0.30% 77.6% Complies 10CFU/g 23.5% 25.1% 50.9% 99.5% |
Conclusion: | Conform with specification |